tert-Butyl carbamate → HCID 59443032, compound

HRID 2380891Notes

Reaction equation

HRID 2380891 reaction equation
Cl[C:2]1[CH:11]=[C:10]2[C:5]([C:6]([C:16]3[CH:21]=[CH:20][C:19]([F:22])=[CH:18][CH:17]=3)=[C:7]([C:14]#[N:15])[C:8]([CH3:13])([CH3:12])[O:9]2)=[CH:4][CH:3]=1.[C:23](=[O:30])([O:25][C:26]([CH3:29])([CH3:28])[CH3:27])[NH2:24]>>[C:14]([C:7]1[C:8]([CH3:13])([CH3:12])[O:9][C:10]2[C:5]([C:6]=1[C:16]1[CH:21]=[CH:20][C:19]([F:22])=[CH:18][CH:17]=1)=[CH:4][CH:3]=[C:2]([NH:24][C:23](=[O:30])[O:25][C:26]([CH3:29])([CH3:28])[CH3:27])[CH:11]=2)#[N:15]

Participants

3

Reactant 2

HCID 77922tert-Butyl carbamateHCID 59442989HCID 59442989, compound

Product 1

HCID 59443032HCID 59443032, compound

Procedure

The compound obtained in (2) described above (340 mg) and tert-butyl carbamate (380 mg) were treated in the same manner as Reference Example 5(4) to give the titled compound (427 mg) as a pale yellow powder.

Sources & evidence

ORD record
ord-824e0ae3bdd04510b12fbfa76f9085c8
Source dataset
uspto-grants-2012_09
Patent number
US08258131B2

Reaction notes

Loading…