tert-Butyl carbamate → HCID 59442967, compound

HRID 2380902Notes

Reaction equation

HRID 2380902 reaction equation
Cl[C:2]1[CH:11]=[C:10]2[C:5]([C:6]([C:17]3[CH:22]=[CH:21][C:20]([F:23])=[CH:19][CH:18]=3)=[C:7]([C:14](=[O:16])[CH3:15])[C:8]([CH3:13])([CH3:12])[O:9]2)=[CH:4][CH:3]=1.[C:24](=[O:31])([O:26][C:27]([CH3:30])([CH3:29])[CH3:28])[NH2:25]>>[C:14]([C:7]1[C:8]([CH3:13])([CH3:12])[O:9][C:10]2[C:5]([C:6]=1[C:17]1[CH:22]=[CH:21][C:20]([F:23])=[CH:19][CH:18]=1)=[CH:4][CH:3]=[C:2]([NH:25][C:24](=[O:31])[O:26][C:27]([CH3:30])([CH3:29])[CH3:28])[CH:11]=2)(=[O:16])[CH3:15]

Participants

3

Reactant 2

HCID 77922tert-Butyl carbamateHCID 59443010HCID 59443010, compound

Product 1

HCID 59442967HCID 59442967, compound

Procedure

The compound obtained in (2) described above (118 mg) and tert-butyl carbamate (130 mg) were treated in the same manner as Reference Example 5(4) to give the titled compound (147 mg) as a yellow powder.

Sources & evidence

ORD record
ord-8ba1c3b70c864639a7abb63520e606cf
Source dataset
uspto-grants-2012_09
Patent number
US08258131B2

Reaction notes

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