HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl iodide → (2-Chloro-quinazolin-4-yl)-(2-methoxy-phenyl)-methyl-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | 2-Chloro-N-(2-methoxyphenyl)quinazolin-4-amine | HCID 22692722 | — |
| Product | (2-Chloro-quinazolin-4-yl)-(2-methoxy-phenyl)-methyl-amine | HCID 11266548 | — |
Reaction Steps
The title compound was prepared from (2-chloro-quinazolin-4-yl)-(2-methoxy-phenyl)-amine and methyl iodide by a procedure similar to example 7 (72% yield). 1H NMR (CDCl3): 7.72 (d, J=8.1 Hz, 1H), 7.54 (ddd, J=8.4, 6.6 and 1.5 Hz, 1H), 7.20 (dd, J=8.4 and 1.8 Hz, 1H), 6.87-7.04 (m, 4H), 3.67 (s, 3H), 3.56 (s, 3H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08258145B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-3fd8934642bb4d8798eeb40fec717990 |
| Source note | uspto-grants-2012_09 |