HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 3-(cyclopentyloxy)-4-methoxy-2-nitrobenzoate → Methyl 2-amino-3-(cyclopentyloxy)-4-methoxybenzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 3-(cyclopentyloxy)-4-methoxy-2-nitrobenzoate | HCID 66781723 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | Methyl 2-amino-3-(cyclopentyloxy)-4-methoxybenzoate | HCID 66781747 | — |
Reaction Steps
A mixture of methyl 3-(cyclopentyloxy)-4-methoxy-2-nitrobenzoate (750 mg, 2.54 mmol), 10% Pd/C (50% H2O, 500 mg, 0.23 mmol Pd), and methanol (10 mL) was stirred vigorously at rt under an atmosphere of H2. After 21 h, the mixture was filtered through Celite and concentrated to give methyl 2-amino-3-(cyclopentyloxy)-4-methoxybenzoate: MS (ESI): 266.5.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08258154B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-fa73410219164886a147c5099fddd8e9 |
| Source note | uspto-grants-2012_09 |