反应详情

Obtained in 60% yield by an analogous method to Example 29, preparation of starting materials, starting from 4-{4-[3-(trifluoromethyl)[1,2,4]triazolo[4,3-b]pyridazin-6-yl]piperazin-1-yl}phenol (obtained as described in Example 16, preparation of starting materials) and tert-butyl 4-(2-hydroxyethyl)piperazine-1-carboxylate (CAS 77279-24-4).

1. customObtained in 60% yield by an analogous method to Example 29, preparation of starting materials