p-Fluoronitrobenzene → Benzenamine,4-[2,2,2-trifluoro-1-(methoxymethyl)ethoxy]-

HRID 2381186Notes

Reaction equation

F[C:2]1[CH:7]=[CH:6][C:5]([N+:8]([O-])=O)=[CH:4][CH:3]=1.[F:11][C:12]([F:19])([F:18])[CH:13]([OH:17])[CH2:14][O:15][CH3:16]>>[F:11][C:12]([F:19])([F:18])[CH:13]([CH2:14][O:15][CH3:16])[O:17][C:2]1[CH:7]=[CH:6][C:5]([NH2:8])=[CH:4][CH:3]=1

Participants

Reactant 2

HCID 9590p-Fluoronitrobenzene

HCID 229134801,1,1-Trifluoro-3-methoxypropan-2-ol

Product 1

HCID 69810939Benzenamine,4-[2,2,2-trifluoro-1-(methoxymethyl)ethoxy]-

Procedure

This material was obtained following the procedures described in example 33 i,ii) from 1-fluoro-4-nitro-benzene and (rac)-1,1,1-trifluoro-3-methoxy-propan-2-ol.

Workup

customThis material was obtained

Sources & evidence

ORD record: ord-8534231d4a4841b796d9d7e05aac1b58
Source dataset: uspto-grants-2012_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08258158B2

Reaction notes

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