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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 23812Generated: October 25, 2026

Ephedrine → Methamphetamine

https://huagongshe.com/reaction/23812

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEphedrineHCID 9294—
ReactantLithiumHCID 3028194—
SolventAmmoniaHCID 222—
ProductMethamphetamineHCID 10836—

Reaction Steps

In the dissolving metal reduction method of methamphetamine synthesis, the ephedrine or pseudo-ephedrine starting ingredient is obtained, often by extraction from over-the-counter cold medication. Anhydrous ammonia is obtained, typically by theft from agricultural supplies. Lithium metal is obtained from lithium batteries. Lithium metal is dissolved in the liquid, anhydrous ammonia to give a blue colored solution, to which ephedrine is added. The ammonia is allowed to boil off leaving the crude, free-base methamphetamine product, which is typically purified by common practice and converted to the hydrochloride salt.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06852891B2
Source datasetuspto-grants-2005_02
ORD IDord-375a7c2d3bf245fabb5ab2182518650a
Source noteuspto-grants-2005_02