HuagongsheHuagongshe Chemistry Print Report · For research reference only
(5-Benzyloxy-2-bromo-4-methoxyphenyl)p-tolylmethanol → (5-Benzyloxy-2-bromo-4-methoxyphenyl)p-tolylmethanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (5-Benzyloxy-2-bromo-4-methoxyphenyl)p-tolylmethanol | HCID 67110063 | — |
| Catalyst | HCID 178418406 | HCID 178418406 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | (5-Benzyloxy-2-bromo-4-methoxyphenyl)p-tolylmethanone | HCID 53629725 | 87.8% |
Reaction Steps
A mixture of 5-benzyloxy-2-bromo-4-methoxyphenyl)-p-tolylmethanol (reference example 9-1) (1.27 g), manganese dioxide (2.67 g) and dichloromethane (30 mL) was stirred at room temperature overnight. Insoluble materials were removed by celite (registered mark) filtration. The filtrate was concentrated under reduced pressure to give the title compound (1.11 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08258162B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-18104ee67ef74a98a7bcfa51e409e93c |
| Source note | uspto-grants-2012_09 |