Methyl Isocyanate → (RS)-S-(4-nitrophenyl)-N-(methylcarbamoyl)-S-methylsulfoximide

Participants

Reaction Conditions

Reaction Steps

300 mg (1.5 mmol) (RS)—S-(4-nitrophenyl)-S-methylsulfoximide in 8 ml toluene and 4 ml petroleum ether 60/80 are treated with 0.097 ml (1.65 mmol) methyl isocyanate. The mixture is stirred in a pressure tube at 104° C. for 5 hours and at room temperature for 14 hours. The suspension is filtrated to give 302 mg (corresponding to 78% of theor.) of the product.

Provenance & Evidence