HuagongsheHuagongshe Chemistry Print Report · For research reference only
(RS)-S-(4-nitrophenyl)-N-(methylcarbamoyl)-S-methylsulfoximide → (RS)-S-(4-aminophenyl)-N-(methylcarbamoyl)-S-methylsulfoximide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (RS)-S-(4-nitrophenyl)-N-(methylcarbamoyl)-S-methylsulfoximide | HCID 59550870 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | (RS)-S-(4-aminophenyl)-N-(methylcarbamoyl)-S-methylsulfoximide | HCID 59550841 | — |
Reaction Steps
302 mg (1.17 mmol) (RS)—S-(4-nitrophenyl)-N-(methylcarbamoyl)-S-methylsulfoximide in 20 ml methanol is hydrogenated over 60 mg palladium (10% on carbon, 50% water wet) for 4 hours at 26° C. and 30 bar. The catalyst is filtered and the solvent evaporated to give 271 mg (corresponding to 100% of theor.) of the product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08642611B2 |
| Source dataset | uspto-grants-2014_02 |
| ORD ID | ord-960c30a9466b4919ad90f83963fd98bf |
| Source note | uspto-grants-2014_02 |