HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trimethylsilylacetylene → 6-(trimethylsilyl)ethynyl-1H-indazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trimethylsilylacetylene | HCID 66111 | — |
| Reactant | 6-iodo-1H-indazole | HCID 12991241 | — |
| Product | 6-(trimethylsilyl)ethynyl-1H-indazole | HCID 68744567 | 77% |
Reaction Steps
6-Iodo-1H-indazole (1.00 g, 4.10 mmol) was reacted with trimethylsilyl acetylene (0.61 mL, 4.30 mmol) in analogy to GP8a to give 675 mg (77%) of pure 6-(trimethylsilyl)ethynyl-1H-indazole.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08642611B2 |
| Source dataset | uspto-grants-2014_02 |
| ORD ID | ord-ee1820cfd8d141c98654e16a88288dbb |
| Source note | uspto-grants-2014_02 |