HuagongsheHuagongshe Chemistry Print Report · For research reference only
(-)-2,2,2-Trifluoro-1-(9-anthryl)ethanol → (1r)-1-Methylthiocarbonyloxyethyl-2-methylpropanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (-)-2,2,2-Trifluoro-1-(9-anthryl)ethanol | HCID 7006444 | — |
| Reactant | 1-(Methylthiocarbonyloxy)ethyl isobutyrate | HCID 87183506 | — |
| Product | (1r)-1-Methylthiocarbonyloxyethyl-2-methylpropanoate | HCID 87183618 | — |
Reaction Steps
For comparison, racemic 1-methylthiocarbonyloxyethyl-2-methylpropanoate: 1H-NMR in presence of (R)-(−)-2,2,2-trifluoro-1-(9-anthryl)ethanol as chiral solvating agent (CDCl3): δ 1.18 (m, 6H), 1.49 (d, J=5.2 Hz, 1.5H), 1.50 (d, J=5.6 Hz, 1.5H), 2.33 (s, 1.5H), 2.34 (s, 1.5H), 2.55 (septet, J=7.2 Hz, 0.5H), 2.56 (septet, J=7.2 Hz, 0.5H), 6.92 (q, J=5.6 Hz, 0.5H), 6.92 (q, J=5.6 Hz, 0.5H) ppm.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08258179B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-affd37fc6b43430aa60c65f552246d8e |
| Source note | uspto-grants-2012_09 |