Hydroxyamine hydrochloride → 2,3,5-Trichloro-N-[2-(N-formyl-N-hydroxy-amino)-ethyl]-benzamide

関与物質

反応手順

To a solution of 2,3,5-trichloro-N-(2-oxo-ethyl)-benzamide (0.80 g, 3.0 mmol) in MeOH (100 mL) was added hydroxylamine hydrochloride (0.41 g, 6 mmol) and sodium acetate (0.49 g, 6 mmol). The mixture was stirred 18 h and the MeOH was removed in vacuo. The residue was dried in vacuo for 18 h and was used without further purification to yield the title compound (1.4 g) as a white solid. ESMS: M+H=281.

情報源と証拠