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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2381627Generated: November 2, 2026

HCID 57990324, compound → HCID 44467095, compound

https://huagongshe.com/reaction/2381627

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 57990324HCID 57990324—
SolventTrifluoroacetic acidHCID 6422—
ProductHCID 44467095HCID 4446709578.7%

Reaction Steps

A solution of tert-butyl (1-(2-(1H-indazol-6-ylamino)-5-fluoropyrimidin-4-yl)piperidin-2-yl)methylcarbamate (41 mg, 0.093 mmol) in TFA (4 mL) was stirred at room temperature for 60 min. TFA was removed in vacuo. The residue was purified by HPLC to give N-(4-(2-(aminomethyl)piperidin-1-yl)-5-fluoropyrimidin-2-yl)-1H-indazol-6-amine (25 mg) MS 342.3 (M+H); UV 201.8, 246.8, 278.8 nm.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08258144B2
Source datasetuspto-grants-2012_09
ORD IDord-d60461a5ca8b45bc9efe432a7307e498
Source noteuspto-grants-2012_09