Hydrochloride methanol → HCID 86639368, compound

HRID 2381977Notes

Reaction equation

[CH3:1][N:2]1[CH2:7][CH2:6][N:5]([NH:8][C:9]([C:11]2[CH:12]=[N:13][C:14]([C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=3)=[N:15][CH:16]=2)=[O:10])[CH2:4][CH2:3]1.CO.[ClH:25]>>[ClH:25].[ClH:25].[CH3:1][N:2]1[CH2:3][CH2:4][N:5]([NH:8][C:9]([C:11]2[CH:16]=[N:15][C:14]([C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=3)=[N:13][CH:12]=2)=[O:10])[CH2:6][CH2:7]1

Participants

Reactant 2

HCID 21893726Hydrochloride methanol

HCID 25099777HCID 25099777, compound

Product 1

HCID 86639368HCID 86639368, compound

Procedure

2-Phenyl-pyrimidine-5-carboxylic acid (4-methyl-piperazin-1-yl)-amide is dissolved in HCl methanol solution and evaporated methanol to dryness to afford 2-phenyl-pyrimidine-5-carboxylic acid (4-methyl-piperazin-1-yl)-amide dihydrochloride as a solid. MS: 298 (M+H).

Workup

customevaporated methanol to dryness

Sources & evidence

ORD record: ord-ae1133f2e3ff4a1c84eb1d13952739b5
Source dataset: uspto-grants-2012_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08258130B2

Reaction notes

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