Ethyl orthoformate → HCID 178478200, compound

HRID 2382151Notes

Reaction equation

HRID 2382151 reaction equation
[ClH:1].[CH:2]1[C:15]2[C:6](=[N:7][C:8]([NH:16][NH:17][C:18]3[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=3)=[C:9]3[C:14]=2[CH:13]=[CH:12][CH:11]=[CH:10]3)[CH:5]=[CH:4][CH:3]=1.[CH:24](OCC)(OCC)OCC>>[Cl-:1].[C:18]1([N+:17]2[N:16]=[CH:8][N:7]3[C:24]=2[C:9]2[CH:10]=[CH:11][CH:12]=[CH:13][C:14]=2[C:15]2[CH:2]=[CH:3][CH:4]=[CH:5][C:6]3=2)[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1

Participants

3

Reactant 2

HCID 31214Ethyl orthoformateHCID 67128370N-Phenanthridin-6-yl-N'-phenylhydrazine hydrochloride

Product 1

HCID 178478200HCID 178478200, compound

Procedure

A suspension of N-phenanthridin-6-yl-N′-phenylhydrazine hydrochloride (2.0 g, 6.2 mmol) in triethyl orthoformate (100 ml) is stirred under reflux under argon for 17 h. After cooling to room temperature, the mixture is concentrated and the precipitate is filtered off and washed with petroleum ether, methyl tert-butyl ether and acetone. Yield: 1.2 g (57%).

Workup

  1. temperatureunder reflux under argon for 17 h
  2. concentrationthe mixture is concentrated
  3. filtrationthe precipitate is filtered off
  4. washwashed with petroleum ether, methyl tert-butyl ether and acetone

Sources & evidence

ORD record
ord-4359aec09a764eee98023db03f0708e4
Source dataset
uspto-grants-2012_09
Patent number
US08258297B2

Reaction notes

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