HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 68734622, compound → HCID 68734802, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 68734622 | HCID 68734622 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 68734802 | HCID 68734802 | 74.1% |
Reaction Steps
To a solution of (Z)-3-(phenyl(m-tolyl)methylene)pyrrolidine (4.0 g, 16.1 mmol) in methanol (40 mL) at room temperature was added 10% Pd/C (9.5 g) and the contents were hydrogenated at 50 psi hydrogen atmosphere and at room temperature for 12 h. The reaction mixture was filtered through celite bed and the bed was washed with methanol. The filtrate was concentrated under reduced pressure to afford 3.0 g of 3-(phenyl(m-tolyl)methyl)pyrrolidine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08258306B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-f966a1c6f15d4dff87115635d83c9412 |
| Source note | uspto-grants-2012_09 |