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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2382198Generated: November 2, 2026

HCID 68734622, compound → HCID 68734802, compound

https://huagongshe.com/reaction/2382198

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 68734622HCID 68734622—
ReactantHCID 178418361HCID 178418361—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
ProductHCID 68734802HCID 6873480274.1%

Reaction Steps

To a solution of (Z)-3-(phenyl(m-tolyl)methylene)pyrrolidine (4.0 g, 16.1 mmol) in methanol (40 mL) at room temperature was added 10% Pd/C (9.5 g) and the contents were hydrogenated at 50 psi hydrogen atmosphere and at room temperature for 12 h. The reaction mixture was filtered through celite bed and the bed was washed with methanol. The filtrate was concentrated under reduced pressure to afford 3.0 g of 3-(phenyl(m-tolyl)methyl)pyrrolidine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08258306B2
Source datasetuspto-grants-2012_09
ORD IDord-f966a1c6f15d4dff87115635d83c9412
Source noteuspto-grants-2012_09