HuagongsheHuagongshe Chemistry Print Report · For research reference only
Propionic anhydride → HCID 68802816, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Propionic anhydride | HCID 31263 | — |
| Reactant | 2-Amino-5-fluorobenzoic acid | HCID 101412 | — |
| Product | HCID 68802816 | HCID 68802816 | — |
Reaction Steps
A mixture of 2-amino-5-fluorobenzoic acid (23.3 g, 0.15 mol) and propionic acid anhydride (150 mL) was heated to reflux for 3 hr, then the propionic acid anhydride was removed in vacuo to afford 2-ethyl-6-fluoro-benzo[d][1,3]oxazin-4-one 2 as a gray solid, which was used directly in the next step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08642609B2 |
| Source dataset | uspto-grants-2014_02 |
| ORD ID | ord-7dd749abf1754d5eacddc88de5f81d15 |
| Source note | uspto-grants-2014_02 |