HuagongsheHuagongshe Chemistry Print Report · For research reference only
Iodine → 1,2-Dihydro-2,2,4-trimethylquinoline-6-carboxylic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Iodine | HCID 807 | — |
| Reactant | Methyl 4-aminobenzoate | HCID 12082 | — |
| Solvent | Mesityl oxide | HCID 8858 | — |
| Product | 1,2-Dihydro-2,2,4-trimethylquinoline-6-carboxylic acid methyl ester | HCID 53416110 | — |
Reaction Steps
Skraup reaction of methyl 4-aminobenzoate (5.0 g) and iodine (1.7 g) in mesityl oxide (25 ml) was performed according to the method described in example 1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08258293B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-a9e35bb642ed4dbe8c41dc35ddc8bfe1 |
| Source note | uspto-grants-2012_09 |