Acetyl chloride → HCID 17962891, compound

HRID 2382305Notes

Reaction equation

HRID 2382305 reaction equation
[CH2:1]([C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][CH:12]=1)[NH:9][C:8]([CH3:14])([CH3:13])[CH:7]=[C:6]2[CH3:15])[CH3:2].[C:16](Cl)(=[O:18])[CH3:17]>N1C=CC=CC=1>[C:16]([N:9]1[C:10]2[C:5](=[CH:4][C:3]([CH2:1][CH3:2])=[CH:12][CH:11]=2)[CH:6]([CH3:15])[CH2:7][C:8]1([CH3:14])[CH3:13])(=[O:18])[CH3:17]

Participants

4

Reactant 2

HCID 6367Acetyl chlorideHCID 6593886-ethyl-2,2,4-trimethyl-1,2-dihydroquinoline

Product 1

HCID 17962891HCID 17962891, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

Acylation of 1,2-dihydro-6-ethyl-2,2,4-trimethylquinoline (800 mg) with acetyl chloride (3.5 ml) and a catalytic amount of N,N-dimethylaminopyridine in pyridine (25 ml) was performed according to the method described in example 37.

Sources & evidence

ORD record
ord-1c4f459d9b4b484fb4359cbaa033fb87
Source dataset
uspto-grants-2012_09
Patent number
US08258293B2

Reaction notes

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