1-Methyl-1h-1,2,3-benzotriazole-5-carbonyl chloride → HCID 66630470, compound

Participants

Role	Name	HCID	Charge
Reactant	1-Methyl-1h-1,2,3-benzotriazole-5-carbonyl chloride	HCID 2776550	—
Reactant	N-{(R)-1-[6-[2,2-Bis-(4-hydroxy-phenyl)-ethylamino]-9-((1R,2S,3R,4S)-2,3-dihydroxy-4-propionylamino-cyclopentyl)-9H-purin-2-yl]-pyrrolidin-3-yl}-isonicotinamide hydrochloride	HCID 66629861	—
Product	HCID 66630470	HCID 66630470	—

Reaction Steps

This compound is prepared analogously to N-{(R)-1-[6-[2,2-Bis-(4-hydroxy-phenyl)-ethylamino]-9-((1R,2S,3R,4S)-2,3-dihydroxy-4-propionylamino-cyclopentyl)-9H-purin-2-yl]-pyrrolidin-3-yl}-isonicotinamide hydrochloride (Example 158) by replacing isonicotinoyl chloride hydrochloride with 1-methyl-1H-1,2,3-benzotriazole-5-carbonyl chloride. (MH+ 762.4)

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08258141B2
Source dataset	uspto-grants-2012_09
ORD ID	ord-3049cf3ec55a45d195f89cb501dc6637
Source note	uspto-grants-2012_09