HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl iodide → 2-(Methylthio)benzoxazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | 1,3-benzoxazole-2-thiol | HCID 178418282 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 2-(Methylthio)benzoxazole | HCID 4178773 | — |
Reaction Steps
Methyl iodide (20 mL, 320 mmol) was added to a solution of benzooxazole-2-thiol (25.0 g, 165 mmol) taken in dry THF (250 mL) and the reaction mixture was stirred at room temperature for 80 hours, after which it was concentrated to give 2-methylsulfanyl-benzooxazole.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08263587B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-516d14933b2447c18e7bbc2a2b38d4d3 |
| Source note | uspto-grants-2012_09 |