HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,3-Benzodioxol-5-amine → N-Benzo[1,3]dioxol-5-yl-5-chloro-2-trifluoromethyl-benzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,3-Benzodioxol-5-amine | HCID 84310 | — |
| Reactant | 5-Bromo-2-chlorobenzene-1-sulfonyl chloride | HCID 50988834 | — |
| Reactant | 5-Chloro-2-(trifluoromethyl)benzene-1-sulfonyl chloride | HCID 86631903 | — |
| Product | N-Benzo[1,3]dioxol-5-yl-5-chloro-2-trifluoromethyl-benzenesulfonamide | HCID 68722727 | — |
Reaction Steps
This compound is prepared analogously to Intermediate E (step 2) by replacing S-bromo-2-chloro-benzenesulfonyl chloride with 5-chloro-2-trifluoromethyl-benzenesulfonyl chloride and by replacing aniline with 3,4-(methylenedioxy)aniline to afford the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08263585B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-03f55a55a56446ecb4f5cc7a3291134d |
| Source note | uspto-grants-2012_09 |