Hydrochloric Acid → HCID 67059989, compound

Participants

Reaction Conditions

Reaction Steps

4-(2-Nitrophenyl)-3,6-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester (0.45 g) was dissolved in a solution of hydrogen chloride in dioxane (4 N, 4 mL). After stirring for 0.5 hour at 50° C., the solvent was removed by evaporation and the residue triturated with diethyl ether to give the title compound as a white solid (0.29 g). LCMS m/z 205.2 [M+H]+. R.T.=3.80 min (Analytical Method 4).

Provenance & Evidence