1-Acetylpiperidine-4-carbonyl chloride → 1-acetyl-N-[5-(3-furyl)[1,2,4]triazolo[1,5-a]pyridin-2-yl]piperidine-4-carboxamide

Participants

Reaction Steps

The title compound was prepared following procedure and work up described for example 19, but starting from 5-(3-furyl)[1,2,4]triazolo[1,5-a]pyridin-2-amine ((A2), 50 mg; 0.25 mmol; 1.0 eq.) and 1-acetylpiperidine-4-carbonyl chloride (57 mg; 0.3 mmol; 1.2 eq.) as a white powder (41.3 mg, 46%). HPLC, Rt: 2.15 min. (purity 93.3%). LC/MS, M+(ESI): 354.4, M−(ESI): 352.4.

Provenance & Evidence