Tetrahydrofurfurylamine → N-{5-[(tetrahydrofuran-2-ylmethyl)amino][1,2,4]triazolo[1,5-a]pyridin-2-yl}benzamide

Participants

Reaction Steps

The title compound was prepared following procedure described for example 30 but starting from N-(5-chloro[1,2,4]triazolo[1,5-a]pyridin-2-yl)benzamide ((B3), 50 mg; 0.18 mmol; 1.0 eq.) and tetrahydrofurfurylamine (1.0 mL) as a white powder (32 mg, 52%). HPLC, Rt: 2.34 min. (purity 91.7%). LC/MS, M+(ESI): 339.0, M−(ESI): 338.1.

Provenance & Evidence