Cycloheptylamine → HCID 67529063, compound

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Reaction Steps

The title compound was prepared following procedure described for example 30 but starting from N-(5-chloro[1,2,4]triazolo[1,5-a]pyridin-2-yl)nicotinamide ((B4), 296 mg; 1.08 mmol; 1.0 eq.) and cycloheptylamine (1.0 mL). The parent compound was dissolved in MeOH and Et2O/HCl was added. The precipitate obtained was filtered, washed with Et2O and dried under reduced pressure at 40° C. to give the title compound as a white powder (178 mg, 42%). HPLC, Rt: 2.98 min. (purity 99.7%). LC/MS, M+(ESI): 351.4, M−(ESI): 349.4. CHN analysis: [C19H22N6O.2.0 HCl.1.5H20] Corrected: C, 50.67%; H, 6.04%; N, 18.66%. Found: C, 50.69%; H, 5.97%; N, 18.61%.

Provenance & Evidence