HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Methyl-2-furylmethylamine → N-(5-{[(5-methyl-2-furyl)methyl]amino}[1,2,4]triazolo[1,5-a]pyridin-2-yl) nicotinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Methyl-2-furylmethylamine | HCID 2724683 | — |
| Reactant | N-(5-bromo[1,2,4]triazolo[1,5-a]pyridin-2-yl)nicotinamide | HCID 25212514 | — |
| Product | N-(5-{[(5-methyl-2-furyl)methyl]amino}[1,2,4]triazolo[1,5-a]pyridin-2-yl) nicotinamide | HCID 59437542 | — |
Reaction Steps
The title compound was prepared following procedure described for example 30 but starting from N-(5-bromo[1,2,4]triazolo[1,5-a]pyridin-2-yl)nicotinamide ((B2), 100 mg; 0.31 mmol; 1.0 eq.) and 5-methylfurfurylamine (1.0 mL) as an off-white solid (40 mg, 37%). HPLC, 2.38 min. Rt: (purity 98.6%). LC/MS, M−(ESI): 347.1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08263595B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-a2397d0d9bfd4500938a5b86f5bdf9cd |
| Source note | uspto-grants-2012_09 |