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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2382868Generated: November 4, 2026

Cyclopropanemethanamine → HCID 59437447, compound

https://huagongshe.com/reaction/2382868

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclopropanemethanamineHCID 75646—
ReactantHCID 25212520HCID 25212520—
ProductHCID 59437447HCID 59437447—

Reaction Steps

The title compound was prepared following procedure described for example 85, but starting from N-[5-chloro-7-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyridin-2-yl]nicotinamide ((B7), 50 mg; 0.15 mmol; 1.0 eq.) and (aminomethyl)cyclopropane (52 μl; 0.73 mmol; 5.0 eq.) as a white solid (43 mg, 78%). HPLC, Rt: 3.19 min. (purity 78.6%). LC/MS, M+(ESI): 420.0, M−(ESI): 418.0.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08263595B2
Source datasetuspto-grants-2012_09
ORD IDord-7187b6ab3bbc4e7b87c64ec327afef28
Source noteuspto-grants-2012_09