HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclopropanemethanamine → HCID 59437447, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclopropanemethanamine | HCID 75646 | — |
| Reactant | HCID 25212520 | HCID 25212520 | — |
| Product | HCID 59437447 | HCID 59437447 | — |
Reaction Steps
The title compound was prepared following procedure described for example 85, but starting from N-[5-chloro-7-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyridin-2-yl]nicotinamide ((B7), 50 mg; 0.15 mmol; 1.0 eq.) and (aminomethyl)cyclopropane (52 μl; 0.73 mmol; 5.0 eq.) as a white solid (43 mg, 78%). HPLC, Rt: 3.19 min. (purity 78.6%). LC/MS, M+(ESI): 420.0, M−(ESI): 418.0.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08263595B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-7187b6ab3bbc4e7b87c64ec327afef28 |
| Source note | uspto-grants-2012_09 |