HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Pyridinecarbonyl chloride, hydrochloride (1:1) → HCID 59437509, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Pyridinecarbonyl chloride, hydrochloride (1:1) | HCID 88438 | — |
| Reactant | HCID 25216188 | HCID 25216188 | — |
| Product | HCID 59437509 | HCID 59437509 | — |
Reaction Steps
The title compound was prepared following procedure and work up described for intermediate B1 but starting from 5-(cyclohexyloxy)[1,2,4]triazolo[1,5-a]pyridin-2-amine ((A11), 268 mg; 1.15 mmol; 1.0 eq.) and nicotinoyl chloride hydrochloride (247 mg; 1.38 mmol; 1.2 eq.) as an off-white foam (230 mg, 59%). HPLC, Rt: 2.36 min. (purity 94.7%). LC/MS, M−(ESI): 336.1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08263595B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-ac40d5de7dd848d3970087fac7bce4c2 |
| Source note | uspto-grants-2012_09 |