Dimethylformamide → HCID 86643869, compound

Participants

Reaction Conditions

Reaction Steps

To a suspension of potassium 6-(hydroxymethyl)pyridine-3-carboxylate (96 mg; 0.50 mmol; 1.0 eq.) in DCM (1 mL) was added DMF (0.07 mg; 0.02 eq., 0.01 mmol). The mixture was chilled at 0° C. Then oxalyl chloride (317 mg; 2.5 mmol; 5.0 eq.) was added dropwise and the resulting mixture was stirred 4 h at rt. Evaporation of the solvent gave a black line powder without further purification in the next step.

Provenance & Evidence