反应详情

温度

120 °C

The title compound was prepared following procedure and work up described for example 118, but starting from N-[5-chloro-7-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyridin-2-yl]nicotinamide ((B7), 50 mg; 0.14 mmol; 1.0 eq) and dimethylamine (43.0 μL; 0.73 mmol; 5.0 eq), heated at 120° C., to give the title compound as a white solid (20 mg, 39%). HPLC, Rt: 2.52 min. (purity 99.7%). LC/MS, M+(ESI): 350.8, M−(ESI): 348.9.

1. customThe title compound was prepared