HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → HCID 67538521, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Sodium Methoxide | HCID 10942334 | — |
| Reactant | HCID 67536838 | HCID 67536838 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 67538521 | HCID 67538521 | 100% |
Reaction Steps
A solution of 5-bromo-7,8-dimethoxy-1-phenyl-3,4-dihydroisoquinoline (450 mg), EtOH (30 mL), 10% palladium-supported carbon (80 mg) and 28% sodium methoxide in MeOH (0.1 mL) was stirred under a hydrogen atmosphere at room temperature overnight. The insoluble materials were subjected to filtration and the filtrate was concentrated to obtain 7,8-dimethoxy-1-phenyl-1,2,3,4-tetrahydroisoquinoline (350 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08263607B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-443d869a47ce4f398be7d8e06c05179d |
| Source note | uspto-grants-2012_09 |