HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Aminomethyltetrahydropyran → (6-benzyloxy-3-nitroquinolin-4-yl)(tetrahydro-2H-pyran-4-ylmethyl)amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Aminomethyltetrahydropyran | HCID 2773210 | — |
| Reactant | 6-(Benzyloxy)-4-chloro-3-nitroquinoline | HCID 67050992 | — |
| Product | (6-benzyloxy-3-nitroquinolin-4-yl)(tetrahydro-2H-pyran-4-ylmethyl)amine | HCID 67051048 | — |
Reaction Steps
The method described in Part E of Example 1 can be used to treat 7-benzyloxy-4-chloro-3-nitroquinoline with tetrahydro-2H-pyran-4-ylmethylamine to provide (7-benzyloxy-3-nitroquinolin-4-yl)(tetrahydro-2H-pyran-4-ylmethyl)amine. The same method can be used to treat 6-benzyloxy-4-chloro-3-nitroquinoline with tetrahydro-2H-pyran-4-ylmethylamine to provide (6-benzyloxy-3-nitroquinolin-4-yl)(tetrahydro-2H-pyran-4-ylmethyl)amine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08263594B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-219cf6b14a1e4b1d9636d0d4a028e7ed |
| Source note | uspto-grants-2012_09 |