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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2383288Generated: October 31, 2026

Water → HCID 86615228, compound

https://huagongshe.com/reaction/2383288

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantLithium hydroxide, monohydrateHCID 168937—
ReactantHCID 54753949HCID 54753949—
SolventMethanolHCID 887—
ProductHCID 86615228HCID 8661522885.8%

Reaction Steps

A solution of (S)-4-tert-butoxycarbonylamino-2-hydroxybutyric acid methyl ester (1.52 g, 6.52 mmol) in methanol (20.0 mL) was treated with lithium hydroxide monohydrate (273.8 mg, 6.52 mmol) and water (2.0 mL) for 30 min, concentrated, and dried under vacuum to give a white solid (1.26 g)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08263618B2
Source datasetuspto-grants-2012_09
ORD IDord-ab5695c3b9f84baabef29d2d22ab1863
Source noteuspto-grants-2012_09