HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 86615228, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Lithium hydroxide, monohydrate | HCID 168937 | — |
| Reactant | HCID 54753949 | HCID 54753949 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 86615228 | HCID 86615228 | 85.8% |
Reaction Steps
A solution of (S)-4-tert-butoxycarbonylamino-2-hydroxybutyric acid methyl ester (1.52 g, 6.52 mmol) in methanol (20.0 mL) was treated with lithium hydroxide monohydrate (273.8 mg, 6.52 mmol) and water (2.0 mL) for 30 min, concentrated, and dried under vacuum to give a white solid (1.26 g)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08263618B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-ab5695c3b9f84baabef29d2d22ab1863 |
| Source note | uspto-grants-2012_09 |