Triethylamine → HCID 67308845, compound

Participants

Reaction Steps

To a solution of 4-acetoxy-8-bromo-5-fluoronaphthalene-2-carboxylic acid methyl ester (2.0 g) and triethylamine (0.72 g) in ethyl acetate (60 mL) was added palladium-carbon (600 mg) at room temperature, and the mixture was stirred for 1 hour at the same temperature under a hydrogen atmosphere. The insoluble material was removed by filtering through a Celite pad, and the filtrate was concentrated under reduced pressure. The residue was purified by column chromatography on silica gel (eluent: ethyl acetate/n-hexane) to give the title compound.

Provenance & Evidence