Acetophenone → Acetophenone-(4-iodophenyl)hydrazone

HRID 2383351Notes

Reaction equation

HRID 2383351 reaction equation
[C:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1)(=O)[CH3:2].[I:10][C:11]1[CH:16]=[CH:15][C:14]([NH:17][NH2:18])=[CH:13][CH:12]=1>C(O)(=O)C>[I:10][C:11]1[CH:16]=[CH:15][C:14]([NH:17][N:18]=[C:1]([C:4]2[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=2)[CH3:2])=[CH:13][CH:12]=1

Participants

4

Reactant 2

HCID 7410AcetophenoneHCID 7045914-Iodophenylhydrazine

Product 1

HCID 86638617Acetophenone-(4-iodophenyl)hydrazone

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

A solution of 1.54 g (12.82 mmol) of acetophenone in 10 ml of 50% strength acetic acid is added to a solution of 2.0 g (8.546 mmol) of 4-iodophenylhydrazine in 30 ml of the same solvent. The mixture is stirred at room temperature, and a precipitate is formed. After 30 minutes, the precipitate is filtered off and thoroughly washed with water and then with cyclohexane. The residue is dried under high vacuum. This gives 1.95 g (68% of theory) of the title compound.

Workup

  1. customa precipitate is formed
  2. filtrationthe precipitate is filtered off
  3. washthoroughly washed with water
  4. customThe residue is dried under high vacuum

Sources & evidence

ORD record
ord-1a73ef2dbba74d6e916c71acf13e7b32
Source dataset
uspto-grants-2012_09
Patent number
US08263624B2

Reaction notes

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