3-Acetylpyridine → Methyl 3-pyridyl ketone (4-iodophenyl)hydrazone

HRID 2383356Notes

Reaction equation

[I:1][C:2]1[CH:7]=[CH:6][C:5]([NH:8][NH2:9])=[CH:4][CH:3]=1.[C:10]([C:13]1[CH:14]=[N:15][CH:16]=[CH:17][CH:18]=1)(=O)[CH3:11]>>[I:1][C:2]1[CH:7]=[CH:6][C:5]([NH:8][N:9]=[C:10]([C:13]2[CH:14]=[N:15][CH:16]=[CH:17][CH:18]=2)[CH3:11])=[CH:4][CH:3]=1

Participants

Reactant 2

HCID 95893-Acetylpyridine

HCID 7045914-Iodophenylhydrazine

Product 1

HCID 72535741Methyl 3-pyridyl ketone (4-iodophenyl)hydrazone

Procedure

Analogously to the process described in Example 1A, 5.0 g (21.36 mmol) of 4-iodophenylhydrazine and 3-acetylpyridine give 5.15 g (71% of theory) of the title compound.

Sources & evidence

ORD record: ord-20b49a5c7d36436eb70b174a19ee26c1
Source dataset: uspto-grants-2012_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08263624B2

Reaction notes

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