Di-tert-butyl (9-bromononyl)imidodicarbonate → Di-tert-butyl{9-[4-({3-[cyclohexyl(hydroxy)phenylmethyl]-1H-1,2,4-triazol-1-yl}methyl)-piperidin-1-yl]nonyl}imidodicarbonate

Participants

Reaction Steps

The title compound was prepared from cyclohexyl(phenyl)[1-(piperidin-4-ylmethyl)-1H-1,2,4-triazol-3-yl]methanol (Preparation 20, 300 mg, 0.846 mmol) and di-tert-butyl (9-bromononyl)imidodicarbonate (U.S. Pat. No. 4,167,167, 357 mg, 0.846 mmol) using the same method as described in preparation 5, to give a white foam, in 61% yield, 360 mg.

Provenance & Evidence