Benzenesulfonyl chloride → HCID 59490828, compound

Participants

Reaction Steps

The compound 8-(phenylsulfonyl)-3,6,7,8-tetrahydropyrazolo[4′,3′:5,6]pyrido[3,4-d][1]benzazepine was prepared using 3-(4-methoxybenzyl)-3,6,7,8-tetrahydropyrazolo[4′,3′:5,6]pyrido[3,4-d][1]benzazepine and phenylsulfonyl chloride as described in the 2 step procedure K. The desired compound was obtained as an off-white solid (0.040 g, 18%); 1H NMR (CDCl3, 400 MHz) δ: 8.52 (s, 1H), 8.29 (m, 2H), 7.73 (m, 2H), 7.67-7.50 (m, 6H), 7.00 (dd, J1=1.2 Hz, J2=8.8 Hz, 2H), 6.51 (dd, J1=J2=8.0 Hz, 2H), 6.20 (dd, J1=J2=8.0 Hz, 1H), 4.20 (m, 1H), 3.65 (m, 1H), 2.70 (m, 2H); LCMS [M+H]: 377

Provenance & Evidence