Benzoyl chloride → HCID 59490486, compound

Participants

Reaction Steps

The compound, 8-(phenylcarbonyl)-3,6,7,8-tetrahydropyrazolo[4′,3′:5,6]pyrido[3,4-d][1]benzazepine was prepared using 3-(4-methoxybenzyl)-3,6,7,8-tetrahydropyrazolo[4′,3′:5,6]pyrido[3,4-d][1]benzazepine and bezoyl chloride using the 2 step conditions described in general procedure R to give the desired product as a white solid (0.028 g, 19%). M.p.>150° C.; 1H NMR (CDCl3, 400 MHz) δ: 11.25 (brs, 1H), 8.15 (s, 1H), 8.09 (s, 1H), 7.84 (dd, J1=1.2 Hz, J2=8.0 Hz, 1H), 7.41 (m, 1H), 7.21-7.07 (m, 6H), 6.82 (d, J=7.2 Hz, 1H), 4.74 (m, 1H), 3.92 (m, 1H), 3.00 (m, 2H); LCMS [M+H]: 341.

Provenance & Evidence