Ethyl 3-[(2-amino-4-methyl-5-thiazolyl)thio]propanoate → HCID 57883786, compound
Reaction equation
C([O:3][C:4](=[O:30])[CH2:5][CH2:6][S:7][C:8]1[S:12][C:11]([NH:13][C:14]([N:16]([CH:23]2[CH2:28][CH2:27][CH2:26][CH2:25][CH2:24]2)[CH:17]2[CH2:22][CH2:21][CH2:20][CH2:19][CH2:18]2)=[O:15])=[N:10][C:9]=1[CH3:29])C.C(OC(=O)CCSC1SC(N)=NC=1C)C>>[CH:23]1([N:16]([CH:17]2[CH2:18][CH2:19][CH2:20][CH2:21][CH2:22]2)[C:14](=[O:15])[NH:13][C:11]2[S:12][C:8]([S:7][CH2:6][CH2:5][C:4]([OH:30])=[O:3])=[C:9]([CH3:29])[N:10]=2)[CH2:24][CH2:25][CH2:26][CH2:27][CH2:28]1Participants
3
Procedure
Prepared as described in general procedures (A) and (B) using 3-[2-(3,3-dicyclohexyl-ureido)-4-methyl-thiazol-5-ylsulfanyl]-propionic acid ethyl ester and 3-(2-amino-4-methylthiazol-5-ylsulfanyl)-propionic acid ethyl ester
Workup
- customPrepared
Sources & evidence
- ORD record
- ord-e5e651f539f04e88a0a9f1b02180e5a4
- Source dataset
- uspto-grants-2012_09
- Patent number
- US08263634B2
Reaction notes
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