3-(5-Bromo-thiazol-2-yl)-1-cyclopentyl-1-(4-methyl-cyclohexyl)-urea → HCID 57883871, compound

HRID 2384153Notes

Reaction equation

HRID 2384153 reaction equation
Br[C:2]1[S:6][C:5]([NH:7][C:8](=[O:22])[N:9]([CH:17]2[CH2:21][CH2:20][CH2:19][CH2:18]2)[CH:10]2[CH2:15][CH2:14][CH:13]([CH3:16])[CH2:12][CH2:11]2)=[N:4][CH:3]=1.[CH2:23]([O:25][C:26]([C:28]1[N:29]([CH3:34])[C:30]([SH:33])=[N:31][CH:32]=1)=[O:27])[CH3:24]>>[CH2:23]([O:25][C:26]([C:28]1[N:29]([CH3:34])[C:30]([S:33][C:2]2[S:6][C:5]([NH:7][C:8]([N:9]([CH:17]3[CH2:21][CH2:20][CH2:19][CH2:18]3)[CH:10]3[CH2:15][CH2:14][CH:13]([CH3:16])[CH2:12][CH2:11]3)=[O:22])=[N:4][CH:3]=2)=[N:31][CH:32]=1)=[O:27])[CH3:24]

Participants

3

Reactant 2

HCID 578837063-(5-Bromo-thiazol-2-yl)-1-cyclopentyl-1-(4-methyl-cyclohexyl)-ureaHCID 178469865HCID 178469865, compound

Product 1

HCID 57883871HCID 57883871, compound

Procedure

Prepared as described in general procedure (E) using 3-(5-bromo-thiazol-2-yl)-1-cyclopentyl-1-(4-methyl-cyclohexyl)-urea (Example 202) and 2-mercapto-3-methyl-3H-imidazole-4-carboxylic acid ethyl ester.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-a46287da087049308dbfc7a77cee1327
Source dataset
uspto-grants-2012_09
Patent number
US08263634B2

Reaction notes

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