HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyrazolidin-3-one hydrochloride → HCID 57883965, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyrazolidin-3-one hydrochloride | HCID 2733712 | — |
| Reactant | Sodium triacetoxyborohydride | HCID 5049666 | — |
| Reactant | 1,1-Dicyclohexyl-3-(5-formyl-thiazol-2-yl)-urea | HCID 57883471 | — |
| Product | HCID 57883965 | HCID 57883965 | 16% |
Reaction Steps
Prepared as described in general procedure (P) using 1,1-dicyclohexyl-3-(5-formyl-thiazol-2-yl)-urea (42 mg. 0.125 mmol), 3-pyrazolidinone hydrochloride (23 mg, 0.188 mmol) and sodium triacetoxyborohydride (40 mg, 0.188 mmol) to afford 8 mg (16%) of the desired product after purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08263634B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-b601b8c8885c4959bbb30ff396c3b338 |
| Source note | uspto-grants-2012_09 |