HuagongsheHuagongshe Chemistry Print Report · For research reference only
Glycine tert-butyl ester hydrochloride → HCID 57883772, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Glycine tert-butyl ester hydrochloride | HCID 2725036 | — |
| Reactant | Sodium triacetoxyborohydride | HCID 5049666 | — |
| Reactant | 1,1-Dicyclohexyl-3-(5-formyl-thiazol-2-yl)-urea | HCID 57883471 | — |
| Product | HCID 57883772 | HCID 57883772 | 68.8% |
Reaction Steps
Prepared as described in general procedure (P) using 1,1-dicyclohexyl-3-(5-formyl-thiazol-2-yl)-urea (67 mg. 0.20 mmol), glycine tert-butyl ester hydrochloride (50 mg, 0.30 mmol) and sodium triacetoxyborohydride (59 mg, 0.28 mmol) to afford 62 mg (68%) of the desired product after purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08263634B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-79ef47ab718248a481db3930744279ff |
| Source note | uspto-grants-2012_09 |