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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2384236Generated: October 25, 2026

L-Alanine methyl ester → [2-(3,3-Dicyclohexylureido)-thiazole-4-carbonylamino)propionic acid methyl ester

https://huagongshe.com/reaction/2384236

Reaction equation

Participants

RoleNameHCIDCharge
ReactantL-Alanine methyl esterHCID 82335—
Reactant2-(3,3-Dicyclohexylureido)-thiazole-4-carboxylic acidHCID 57883604—
Product[2-(3,3-Dicyclohexylureido)-thiazole-4-carbonylamino)propionic acid methyl esterHCID 7672409817%

Reaction Steps

Prepared in 17% yield (44 mg) as described in general procedure (K) from 2-(3,3-dicyclohexylureido)-thiazole-4-carboxylic acid (210 mg, 0.60 mmol) and (S)-alanine methyl ester (HCl salt, 84 mg, 0.6 mmol).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08263634B2
Source datasetuspto-grants-2012_09
ORD IDord-b01653ba081a4460a7140fd648355067
Source noteuspto-grants-2012_09