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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2384249Generated: October 25, 2026

2-(chloromethyl)-4,5-dihydro-1H-imidazole → 1,1-Dicyclohexyl-3-[5-(4,5-dihydro-1H-imidazol-2-ylmethylsulfanyl)-thiazol-2-yl]-urea

https://huagongshe.com/reaction/2384249

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(chloromethyl)-4,5-dihydro-1H-imidazoleHCID 426328—
ReactantDithioerythritolHCID 439352—
Reactant1,1-Dicyclohexyl-3-(5-thiocyanato-thiazol-2-yl)-ureaHCID 86611192—
Product1,1-Dicyclohexyl-3-[5-(4,5-dihydro-1H-imidazol-2-ylmethylsulfanyl)-thiazol-2-yl]-ureaHCID 57883844—

Reaction Steps

Prepared as described in general procedure (H) using 1,1-dicyclohexyl-3-(5-thiocyanato-thiazol-2-yl)-urea, dithioerythritol and 2-chloromethyl-2-imidazoline.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08263634B2
Source datasetuspto-grants-2012_09
ORD IDord-641c9687657c4775b4d9688ac81c251b
Source noteuspto-grants-2012_09