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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2384264Generated: October 30, 2026

HCID 66872161, compound → HCID 57883716, compound

https://huagongshe.com/reaction/2384264

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 66872161HCID 66872161—
Reactant5-Aminothiazole 2-mercaptoacetic acid ethyl esterHCID 86611194—
ReactantHCID 86611218HCID 86611218—
ProductHCID 57883716HCID 57883716—

Reaction Steps

{2-[3-Cyclohexyl-3-(4,4-difluoro-cyclohexyl)-ureido]-thiazol-5-ylsulfanyl}-acetic acid ethyl ester prepared using general procedures (A) and (B) using cyclohexyl-(4,4-difluoro-cyclohexyl)amine and 5-aminothiazole-2-mercaptoacetic acid ethyl ester. Hydrolysis using general procedure (F) gave the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08263634B2
Source datasetuspto-grants-2012_09
ORD IDord-cbc55282ca8545e9b264dd92019aa308
Source noteuspto-grants-2012_09