Methyl iodide → HCID 57883707, compound

HRID 2384265Notes

Reaction equation

HRID 2384265 reaction equation
[CH:1]1([N:7]([C@@H:19]2[CH2:23][CH2:22][N:21]([C:24]([C:26]3[S:27][CH:28]=[CH:29][CH:30]=3)=[O:25])[CH2:20]2)[C:8]([NH:10][C:11]2[S:12][C:13]([S:16][C:17]#N)=[CH:14][N:15]=2)=[O:9])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.SC[C@@H]([C@@H](CS)O)O.CI>>[CH:1]1([N:7]([C@@H:19]2[CH2:23][CH2:22][N:21]([C:24]([C:26]3[S:27][CH:28]=[CH:29][CH:30]=3)=[O:25])[CH2:20]2)[C:8]([NH:10][C:11]2[S:12][C:13]([S:16][CH3:17])=[CH:14][N:15]=2)=[O:9])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1

Participants

4

Reactant 3

HCID 6328Methyl iodideHCID 439352DithioerythritolHCID 86611219HCID 86611219, compound

Product 1

HCID 57883707HCID 57883707, compound

Procedure

Prepared as described in general procedure (H) using 1-cyclohexyl-3-(5-thiocyanato-thiazol-2-yl)-1-[1-(thiophene-2-carbonyl)-pyrrolidin-3(R)-yl]-urea, dithioerythritol and methyliodide.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-bda5984fd782476aaeaafb2278d3040a
Source dataset
uspto-grants-2012_09
Patent number
US08263634B2

Reaction notes

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