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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2384300Generated: October 27, 2026

2-Aminothiazole → 1-Cyclohex-3-enyl-1-cyclohexyl-3-thiazol-2-yl-urea

https://huagongshe.com/reaction/2384300

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-AminothiazoleHCID 2155—
ReactantCyclohexanoneHCID 7967—
ReactantBis-(1H-imidazol-2-YL)-methanoneHCID 5250894—
ReactantCyclohex-3-en-1-amineHCID 13040867—
Product1-Cyclohex-3-enyl-1-cyclohexyl-3-thiazol-2-yl-ureaHCID 11415501—
ProductCyclohex-3-enyl-cyclohexylamineHCID 65702898—

Reaction Steps

Cyclohex-3-enyl-cyclohexylamine was prepared by reductive amination of cyclohex-3-enylamine and cyclohexanone using general procedure (B). Reaction with carbonyl diimidazole and 2-aminothiazole using general procedure (A) gave the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08263634B2
Source datasetuspto-grants-2012_09
ORD IDord-2b43f48a32914de4a26ee08b26135aef
Source noteuspto-grants-2012_09